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Product Info Summary
| SKU: | M02367 |
|---|---|
| Size: | 100 μl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-EAAT3 Monoclonal Antibody
SKU/Catalog Number
M02367
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-EAAT3 Monoclonal Antibody catalog # M02367. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-EAAT3 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02367)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
AFBG-19
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human EAAT3 Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M02367 is reactive to SLC1A1 in Human, Mouse, Rat
Applications
M02367 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
55 kDa
Calculated molecular weight
57.1kDa
Background of EAAT3
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:1000-1:5000
IHC 1:100-1:500
ICC/IF 1:50-1:200
Validation Images & Assay Conditions
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Western blot analysis of EAAT3 expression in Human fetal brain lysate.
Protein Target Info & Infographic
Gene/Protein Information For SLC1A1 (Source: Uniprot.org, NCBI)
Gene Name
SLC1A1
Full Name
Excitatory amino acid transporter 3
Weight
57.1kDa
Superfamily
dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family
Alternative Names
EAAC1excitatory amino acid carrier 1; EAAT3excitatory amino acid transporter 3; Excitatory amino-acid carrier 1; Neuronal and epithelial glutamate transporter; Sodium-dependent glutamate/aspartate transporter 3; solute carrier family 1 (neuronal/epithelial high affinity glutamatetransporter, system Xag), member 1; Solute carrier family 1 member 1 SLC1A1 DCBXA, EAAC1, EAAT3, SCZD18 solute carrier family 1 member 1 excitatory amino acid transporter 3|excitatory amino acid carrier 1|neuronal and epithelial glutamate transporter|sodium-dependent glutamate/aspartate transporter 3|solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC1A1, check out the SLC1A1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC1A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-EAAT3 Monoclonal Antibody (M02367)
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No publications found for M02367
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Customer Reviews
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